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Published on Feb 19, 2014
Table of Contents: 00:09 Lecture 3.11:Cantilever Sensors - Static Response 01:07 Outline 01:54 Reversal of frequency at nanoscale 03:30 Broadening of frequency response 04:38 Frequency change due to damping (in water) in response to Transient Input 06:38 Outline 07:23 Static deflection can be measured 08:24 Static detection: At your supermarket 10:03 An Example: Mass-induced deflection 12:29 Static vs. dynamic response 13:54 Displacement with an static force 16:21 Spring-softening 19:59 Pull-in instability 23:40 Energy Landscape of Spring weakening 24:54 Conclusions
This course provides an in-depth analysis of the origin of the extra-ordinary sensitivity, fundamental limits, and operating principles of modern nanobiosensors. The primary focus is the physics of biomolecule detection in terms of three elementary concepts: response time, sensitivity, and selectivity. And, it potentiometric, amperometric, and cantilever-based mass sensors to illustrate the application of these concepts to specific sensor technologies.