 The Competency Index for Clinical Research Professionals, CICRPII, is a validated self-assessment tool used to measure the competencies of clinical research coordinators, CRCs. It consists of two factors, one measuring routine clinical research functions and the other measuring advanced clinical functions. The tool can be used to compare the competencies of CRCs working in different research settings, such as those at research intensive CTSA hubs versus those at less intensive community-based sites. Additionally, the tool can be used to gauge an individual's preparedness to function in the role of CRC and to evaluate the effectiveness of clinical research education and training programs. This article was authored by Carlton A. Hornung, Philippe Ianni, Caroline T. Jones, and others.