 Microbial pathogens have caused great harm to the world due to their pathogenicity and ability to spread rapidly in communities. Conventional laboratory-based diagnostics of microbes such as bacteria and viruses require bulky, expensive equipment and highly trained personnel, limiting their usage in resource-limited settings. Biosensors-based point of care, POC, diagnostics have shown great promise in detecting microbial pathogens quickly, cheaply, and easily. Transducers such as electrochemical and optical are used alongside microfluidic integrated biosensors to increase the sensitivity and specificity of detection. Furthermore, microfluidic-based biosensors provide the advantage of being able to detect multiple analytes in small volumes of fluid, making them ideal for portable, integrated platforms. This review discusses the design and fabrication of POC devices for the detection of microbial pathogens, including bacteria, viruses, fungi, and parasites. The integration of electrochemical techniques into microfluidic-based biosensors has been highlighted, as well as current advancements in the field of biosens. This article was authored by Arpana Perihar, Shalu Yadav, Mohamed Abubakar Siddiq and others. We are article.tv, links in the description below.