 Hi, this is Jimin Wen. Welcome to my video abstract on my recent paper. My paper is on protein claustrophic, specifically on X-ray radiation induced action addition to the protein residues. I had a great pleasure writing this paper, making this video abstract. I hope you will enjoy reading my paper, watching this video. Some 30 years ago, I first observed enzyme recover from dissolved crystal after exposure to X-ray radiation for data collection was completely broken down into small pieces, with no intact molecule left. Many examples follow in the last 30 years. I present in this paper, high quality electron density maps. My map was rediscovered three years after I initially obtained because they made no sense to me at that time. Moreover, this map are generally the new direct methods. A leap of faith was needed to trust those maps. I sent two students who gave inspiration for careful re-examination of my map. One is a very bright, inquisitive undergraduate student, Carissa Lettichoff, who asked me to explain phantom reaction through a mechanism of free electrical chain reaction for her chemistry lab work. The other is Jessica Wuzha, a PhD student in chemistry department, Yale University, who asked me to exam some features in the enzyme that require high quality electron density maps. My map show, oxygen atom has been added to many protein residues, for example, alanine residue convert the serine residues, which is completely unexpected. A take-home message is that, sometimes, we have to think outside the confined box of acknowledges. Trust your data, trust your instinct. At the last, I thank Professor Peter Moore for insightful discussion on the subject for his help during dissemination of my results. Finally, thank you for watching the videos. Bye.