 Pemphigoi gestationis is a rare autoimmune disease associated with pregnancy that presents with severe paritis and vesiculobulus lesions, usually beginning on the trunk and spreading rapidly to other parts of the body, including mucosal lesions and facial involvement. This article discusses three cases of PG and their clinical pathological features and management. This article was authored by Stephanie Cohen, Lindsey C. Strode and Rita O. Pichardo.