 The European Commission for the control of foot-and-mouth disease, EUFMD, is continuously seeking for the new possibilities to contribute to early detection, surveillance and outbreak management of FMD and similar transboundary animal diseases. The use of drones in risk and affected areas is such a possibility. Drones allow to obtain real-time data and biological parameters in wider areas without disturbing animals and introduction of biosecurity risk. Drones can capture the farm structure and surrounding area, its borders, establishments, feeding and watering points of animals, and neighboring farms. Drones can get quite close to animals without upsetting them. In this way, clinical signs of infectious disease can be observed and recognized. Drones can be useful for inspection of multiple farms in a short time of animals on pasture and for control and verification of the measures during outbreak management. Drones can also be used to find animal carcasses, monitor movement of animals and wildlife, identify risk contacts with other herds and wildlife, and if equipped with a thermal camera, they can detect animals that have perexia. Overall, the use of drones could make surveillance and control activities much more efficient and fully achieve the goal of maintaining biosecurity to the highest professional level. This is an excellent example how new technologies can support field activities in practice.