 Layered double hydroxide, LDH, materials have been used for controlled drug delivery due to their biocompatibility and porous structure. Recent advancements in the synthesis of intercalated structures have led to increased applications of these materials in biotechnology and medicine. Modification and or functionalization of LDHs has enabled the development of novel biotechnological and biomedical applications. The review focuses on three main areas, i. a cardiovascular drugs, 2. anti-inflammatory drugs, and 3. anti-cancer drugs. Future prospects for LDH-based drug carriers are also discussed. This article was authored by Shwebai, Huizhong, and Li Guangdou.