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Published on Feb 19, 2014
Table of Contents: 00:09 Lecture 2.8: First Passage and Narrow Escape Time 01:43 Outline 02:45 On Cells and Sensors 05:31 Settling time, MFPT, and NET 07:13 Outline 07:28 Response Time vs. First Passage Time 09:09 Charge Control: First Passage Time 10:55 MFPT and Diffusion Capacitance 13:05 Outline 13:06 Example 1: MFPT by Charge Control 16:22 Example 1: MFPT in 1D by Capacitance 18:22 Example 2: MFPT in 3D 20:36 Example 2: MFPT in 3D by Capacitance
This course provides an in-depth analysis of the origin of the extra-ordinary sensitivity, fundamental limits, and operating principles of modern nanobiosensors. The primary focus is the physics of biomolecule detection in terms of three elementary concepts: response time, sensitivity, and selectivity. And, it potentiometric, amperometric, and cantilever-based mass sensors to illustrate the application of these concepts to specific sensor technologies.