 Hematological cancers represent about 10% of all cancers and are characterized by high rates of recurrence, and unpredictable relapses despite improvements in diagnosis and treatments. Medicinal plants and their bioactive compounds offer potential alternatives for treating these cancers, with the ability to reduce tumor growth through multiple mechanisms including apoptosis induction, gene expression modulation, signaling pathway inhibition, and blockage of the cell cycle. Nine bioactive compounds, quercetin or solic acid, phizetin, resveratrol, epigallicatechin-galate, curcumin, gambogic acid, bution, and cellistrol, were identified as having potential applications in chemo-preventive strategies against hematological cancers. This article was authored by Emeka J. Iwala, Adarosekin E. Aliyua Pulumi, Omormime E. Dania, and others. We are article.tv, links in the description below.