 Wilson's disease is an inherited disorder caused by a deficiency of the enzyme ATP7a, which leads to accumulation of copper in the body. Diagnosis can be difficult due to the lack of specific symptoms and the presence of other diseases with similar symptoms. However, laboratory testing can help identify Wilson's disease, including measuring levels of copper in the blood and liver, as well as measuring the amount of copper in ceruloplasmin, a protein that binds copper in the blood. Additionally, newer techniques such as direct measurement of copper exchange or the ratio of copper exchange to total serum copper can also be used to diagnose Wilson's disease. Treatment options include chelation therapy, which involves administering drugs that bind to copper and remove it from the body and liver transplantation. This article was authored by Grzina Gromadska, Marta Greikin, and Adam M. Przebillkowski.