 I am Dr. Pankaj Singhay, Senior Consultant, Interim Medicine, Manipal Hospital, Bangalore. Since all of us we know about that, we are celebrating the immunization program in Manipal Hospital. So, first of all we should know what is the meaning of immunization. Immunization means like getting vaccinated to prevent yourself from the protection of diseases. And you are going to protect others as well. So, we have a significant number of increased death in recent past and nowadays also. So, globally thousands of people are dying because of the severe infectious diseases. And thousands more end up hospitalization because of the severe infectious diseases. So, vaccines are the best way to prevent these diseases. So, we have different guidelines and recommendations of the adult immunization program compared to the children. So, if you compare with the WHO and US adult immunization program, we are little different than the other world. So, recommendation for the adult people in India, like everybody should get vaccinated for DPP, MMR, Influenza, pneumococcal and other vaccines also. And people who are at high risk, they should be get vaccinated because for the typhoid, hepatitis A, hepatitis B, chickenpox, that means very seldom. So, the one should get vaccinated not only going to prevent the infection disease in the particular population. At the same time, it's spreading of the diseases of other people around us. So, I would like to emphasize about the pneumococcal disease and vaccines. So, pneumococcal is a very mortal disease in the form of the pneumonia. Involvement of the layer of the brain and spinal cord, that's meningitis, infection of the ear, that is otitis media. And then, infection of the bloodstream, that is bacteria. So, best way to prevent these diseases are vaccines. So, we have two vaccines available for pneumococcal diseases. First one is a PCV, that is pneumococcal conjugate vaccine 30. It protects for the 13 strains of the pneumococcal bacteria. And another vaccine is the PPSV, that is pneumococcal polysaccharide vaccine 23. It protects the 23 strains of the pneumococcal bacteria. And who should get vaccinated? So, a person who is more than age of 65 years, they should get vaccinated with this PCV 30 followed by PPSV 23 one year later. And population more than age of 19 years should get vaccinated if they have a certain medical condition like infectious diseases, immunological diseases like SLE, lupus erythritus, rheumatoid arthritis, scleroderma, polymyositis, dermatomyositis, liver diseases, kidney diseases, diabetes and neurological diseases like stroke. So, people who are more than age of 19 years with some of the immunocompromised condition or at higher risk, they should get vaccinated. First goes with the PCV 30 followed by PPSV 23 after the eight weeks of gap. And who should not get vaccinated with this pneumococcal vaccine? Either at the, they have a history of allergic reaction to the same vaccine or a reaction to the vaccine which contains the diphtheria toxide that is Tdap. Or people who have acute illness like viral fever, cough cold or any acute clinical condition or crisis. And what are the possible side effects you should monitor? Like person may have a pain, inflammation at the site of injection, redness or tenderness of pain. And generalized symptoms like fever, weight loss, loss of appetite or some of the joints pain especially in shoulders, they are not able to get rid of that. Hence, and then in terms of pregnancy, although there is no harm getting the vaccinated pregnancy, but you should be cautious in pregnancy. But ideally should be get vaccinated before pregnancy. So would like to conclude that since pneumococcal disease is very modern especially in elderly population or young population more than age of 19 years especially in immunocompromised condition. So this pneumococcal vaccine not only going to prevent yourself of the pneumococcal disease at the same time which is going to control the further deterioration or worsening of the primary medical condition. Thank you.