 Prostate cancer, PCA, is typically characterized by a slow growth rate and low metastasis potential. However, some cases of PCA are aggressive and can spread quickly, leading to poor prognosis. In this study, researchers identified two distinct subtypes of PCA based on their differences in cell membrane tension. They found that one subtype was associated with a higher risk of biochemical recurrence compared to the other. Additionally, they discovered that the two subtypes differed in terms of gene expression, mutations, and immune system activity. This suggests that these two subtypes may have different underlying biological processes and could potentially lead to different treatment strategies. This article was authored by DiCiao Feng, Jia Wang, Xu Xia, and others.