 Good morning. We're gonna start a little bit early For those of you who I haven't met my name is Dan Rodin and I'm from Vanderbilt But I have been tasked to to organize this meeting I was looking at at the minutes and and actually some of the videos of the of the previous meetings and And I want to reiterate something that Rex had said at one of the previous meetings and that is that It seemed it was two years ago less than two years ago that there was a Retreat to plan a strategic plan for NHGRI at early house and there was a vigorous debate at that point about whether Genomics was ready for implementation or whether the Institute should ignore that implementation stuff and focus on Genome science, which is what they had done and it's sort of hard to think that that debate happened when you Think look when you look around this room and think about the projects that each of us are thinking about and and doing so It was less than a year ago that a smaller group than this met at Edo hair not not at the Hilton at and another we couldn't get into the Hilton that time and Started a series of meetings on genomic medicine. So the notion is to identify directions and priorities for the field and and really one way to think about it is to give Eric Green and his Associates advice on how NHGRI Should support and accelerate progress in this area and there are lots of possibilities and they're listed here and I won't read them to you So the first meeting a year ago focused on what's really going on in the field We had presentations from about 30 groups that had a whole range of activities and many of you were were there And I will remember those of you who weren't you can go to the web or go to the go to the minutes the second meeting was in Bethesda in December and The notion there was to develop start to develop ideas about multinational multinational multi center collaborative pilot projects in translational Genomic medicine a number of working groups were established and when we'll hear more from the working groups today So the notion is that this meeting should focus on barriers to executing a vision of of using genomic medicine in in the ordinary workflow of healthcare So one of the things that we're going to hear from today one of the constituencies that we're going to hear from today are stakeholders who are outside academic medical centers payers Laboratory medicine people so so that kind of constituency we're also going to Get some lessons from ongoing implementation efforts that are that we haven't heard from before around biomarkers around education the working groups that we've established Will be reporting through the through the day later today and then and then mainly tomorrow and Terry and I have left a Small placeholder at the end for high priority areas for evidence generation and a prelude to the September meeting Teria as I was putting these slides together I couldn't remember whether we had actually set dates and set venues and set hosts no and no Well hosts most likely just to let people know the way that we've been able to fund these is as Supplements to the emerge emerge centers And so with with emerge being where it is probably the next one We'll try to have on the west coast because we're trying to shift them around and there's an emerge site in Seattle So we're aiming for that I think timing is an issue and one that we want to talk to this group about whether we do it In September or maybe wait a little bit do it in December or November December or that sort of thing Okay, so that's so I it's not like I was told and forgot so This meeting Putting together a meeting like this is is not simple There's a lot of give-and-take a lot of conference calls a lot of emails a lot of contacting individuals The people at Vanderbilt who have been particularly instrumental in making sure that you each have a room Making sure that there's a seating plan making sure there's wireless in this room all those things that we all take for granted But can't be taken for granted or Melissa Basterd Robin North and Lauren Ian from NHGRI has been helpful. I didn't see Ian. He's not coming today He's not coming and and then of course all the support we get from NHGRI speaking of which I'm told that I have to announce that those of you who are here on the federal government's dollar We're all here on the federal government's dollar, but those of you who actually work at NIH or Other federal places whose whose travel is supported not by us, but by you There's a meal charge breakfast is $9 lunch is $12 at dinner is $25 the rest of you that's Covered a different way so the planning committee for this In alphabetical order Is listed here. I want to say particular. Thanks to to Terry of course Who's who's done a huge amount of work in and trying to help organize the the details and the big picture? And and I want to give a special shout out to Mark Williams Mark for some reason has a lot of contacts in in the kinds of constituencies that that we wanted to engage today So those of you are here because you were invited by Mark Williams blame him And the rest of us thank him So that's all I wanted to say as a start so that you all know why you're here and what we hope to accomplish And I'll turn the floor over to Eric one