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nanoHUB-U Nanobiosensors L3.2: Sensitivity - Potentiometric Sensors - Charge Screening Planar Sensor

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Published on Feb 19, 2014

Table of Contents:
00:09 Lecture 3.2: Potentiometric Sensors Charge Screening for a Planar Sensor
01:47 Outline
02:54 Sensitivity of a MOSFET-based potentiometric sensor
04:01 DNA binding and Salt screening
05:32 Salt and screening
10:30 How does a Ion-sensitive Field Effect Transistor work (accumulation)
11:27 ISFET in electrolyte ( accumulation)
13:14 Calculating CDL: screening in 1D
16:27 Centroid of DL charge & capacitance
18:05 Screening in 1D
20:28 At high salt concentration (Gouy-Chapman theory)
23:10 Strong screening (perturbative solution)
24:12 Strong screening (perturbative solution)
25:34 Conclusions

This video is part of the nanoHUB-U course "Principles of Electronic Nanobiosensors". (https://nanohub.org/courses/PEN)

This course provides an in-depth analysis of the origin of the extra-ordinary sensitivity, fundamental limits, and operating principles of modern nanobiosensors. The primary focus is the physics of biomolecule detection in terms of three elementary concepts: response time, sensitivity, and selectivity. And, it potentiometric, amperometric, and cantilever-based mass sensors to illustrate the application of these concepts to specific sensor technologies.

For more details see http://nanohub.org/u

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