 Let me introduce the paper soon to be published in biotechnology by engineering. Saxenic acid is prospective building block chemical that should redirect industrial chemistry from using limited hydrocarbons to renewable carbon hydrates. Secretion of a weak organic acid bio-micro result in rapid acidification of the media. And advantages cultivation process require a culture that is resistant to a low pH and high concentration of the product. Such process should be aerobic because maintenance of the cell on the aggressive surrounds like that requires a lot of energy. A living cell may inform the Saxenic acid by three different pathways. In air carrier each of these pathways is located in the separate cellular compartment. The obligatory aerobic East Heroilly Politica does not have fermentation pathways. And the TCA cycle locating in mitochondria indispensably used for energy production at the expense of glucose oxidation. In previous work interruption of TCA cycle on the succinate dehydrogenase reaction allowed us isolating a weakly growing heroist strain. That, however, was able to accumulate 17 grams per liter of Saxenic acid without buffering. In this study we describe a milder step adaptive selection of this strain to improve its property as a producer. A study of assimilation of selected labelled glucose revealed that vast majority of Saxenic acid was formed from the oxidative branch of TCA cycle. Therefore, suppressing the idea that Saxenic acid can be produced as a main product of substrate oxidation along with carbon dioxide. In other words, the vital function of such culture are inextricably linked with the accumulation of the product. And simple improvement of the growth rate under desired conditions should lead to an enhanced productivity. In this regard, the metabolic evaluation experiment was performed that was based on long term cultivation of steady state culture in a bioreactor. During one month's experiment, the control pH was stepwise lowered. The result in a wall strain grew well in a minimal medium, efficiently utilized glucose and accumulated succinic acid at high titer without any pH control. This work was made in the Biological Resource Center Russian National Collection of Industrial Micro-Organisms of the State Research Institute of Genetics. The work is based on the results of investigation of microbial biodiversity and application of the modern methodology of genetic and metabolic engineering to the microorganisms with unique industrial valuable properties, particularly to the east, resistance to high concentration of organic acids. The investigation was supported by a search grant of the Ministry of Science and Education, developing biotechnology of production succinic acid.