 Precision viticulture is experiencing growth due to improved and cost-effective instruments and methodologies for data acquisition and analysis using unmanned aerial vehicles, UAV, which demonstrate low operational costs, high flexibility, and high spatial resolution of imagery compared to traditional platforms such as satellite and aircraft. The aim of this work is to compare NDVI surveys performed with UAV, aircraft, and satellite to assess their capability to represent intravenous vegetation spatial variability. Results indicate that the different platforms provide comparable results in vineyards with coarse vegetation gradients, and large clusters but fail to represent part of the intravenous variability in more heterogeneous vineyards. The cost analysis shows that UAV is advantageous for small areas, and a breakeven point exists above 5 hectares, above such threshold airborne and then satellite have lower imagery cost. This article was authored by Alessandro Matisse, Piero Toscano, Salvatore Filippo Di Genaro, and others.