 The release of Wolbachia-infected mosquitoes is a promising disease intervention strategy that aims to control dengue and other arboviral infections. Early field trials and modeling studies suggest promising epidemiological and entomological outcomes. But the overall cost-effectiveness of the technology is not well studied in a resource-rich setting nor under the suppression approach. This article was authored by Stacy So, Soon Ho Ho, Annabelle Seah, and others.