 The laser scanning confocal microscope made great inroads into biomedical research, but in the mid 90s a new technique called multi-photon microscopy promised great potential in terms of being able to image deep into live samples to look at new processes within biomedical imaging. The difficulty for the people using this technique was that it required a very complicated laser technology called a femtosecond laser, which up until then remained the preserver of the physics labs within universities and large research institutions. Femtosecond lasers require very complicated physics in terms of dispersion control, power control, and pulse width control. It required a physicist generally to be able to maintain the system and to be able to use the equipment required to diagnose and keep the system running. Here at Coherent Scotland we designed the chameleon laser to specifically address this problem. The chameleon product line comprises three different tysaphire lasers and a wavelength extension accessory. The idea of creating the chameleon was to box this ultra-fast laser technology from a breadboard type solution which required continuous twirling of knobs and very complex equipment to monitor the status of the laser and put it in a black box where the biologist could literally turn a key and then set the wavelength that they desire for their imaging. This required a brand new level of automation which has not been seen in such complicated laser technology. There are a wide variety of biological problems which practitioners are using multi-photo microscopy and in fact using chameleon lasers. Imaging in the neurosciences where we can actually look at brain cell structure, we can look at neurons firing, we can observe learning processes. Being able to image deeper within specimens has enabled new techniques particularly in applications like cancer research where physician can look deeper into tissue and observe drug uptakes. Also for tropical medicine where we may be able to observe diseases like malaria and how they progress through the bloodstream. Coherent Scotland will still maintain a philosophy behind its business to take very complicated laser physics and physics-based problems and productise them in a certain way that puts it in the hands of users that can get the most benefit from the technology. Chameleons now can be found in everywhere from hospitals to universities to dedicated imaging core facilities within research centres all over the world from US to the Far East, Australia and we've even sent chameleons as far as Antarctica. The company has now grown to more than 100 employees. We do all the manufacturing here at Coherent Scotland. This is providing jobs both the Scotland and the UK and jobs for physicists as well because the manufacture of these lasers inside is still a very complicated technology. The chameleon and other industrial products have driven growth into the tens of millions of pounds and this has further enabled larger and wider markets like the multi-photo microscopy without this type of laser technology these industries would not have grown. Coherent Scotland is very proud to be of course the first Scottish winner of the Institute of Physics Innovation Award. It's a great accolade for all our employees here have been working hard over the last 10 years to create our success and from Coherent Inc's point of view it certainly adds market goodwill and of course shareholder value.