 The objective of this review is to determine if using the PICO model as a search strategy tool affects the quality of literature searches. A comprehensive literature search was conducted in various databases up until January 9, 2017. Three studies were included and compared PICO to other available models or unguided searching. Due to differences in intervention, no quantitative analysis was performed. The results suggest that few studies exist that assess the effect of the PICO model vis-a-vis other available models or even vis-a-vis the use of no model. Well-designed studies are needed to evaluate the role of the tool used to devise a search strategy before implications for current practice can be drawn. This article was authored by Meta Brand Ericsson and Toe Faber-Francen. We are article.tv, links in the description below.