 We are currently all still stuck in Brazil and those things are actually not looking so well here But in spite of all the challenges, I think we have achieved something quite remarkable that we would like to share here We are kind of tired of what is going on We have all a lot of things to do as we build ventilators We have to deliver ventilators, but one of my colleagues will tell you soon a little bit more about that So I'm in theory we should be actually be stuck at this building here at the moment But of course some of us are at home and only rarely we can access this building But this is where the main research for this project and the main production for this project is going on It's a city building the central interdisciplinary technology as interactive us at the University of São Paulo campus And so the two persons who are there you can now see here in the video So with me there is also Marcelo So Marcelo if you can just kind of give us little wave into the camera and Liza also kind of give a little wave Hello, and so I'm here in this project and in my role as the Caninos Locos Ambassador I'm also as you see Academically in this realm of working with hardware and software But I got in touch with the people who work with the hardware producer to Caninos Locos group here in Brazil And so as you see we have here two of the main heads who are working there So you see here in the middle Marcelo Zufo who is one of the founders of the Caninos Locos group And is the project coordinator in this project we are presenting to you today And also a professor at the electrical engineering department at the University of São Paulo And then we have Liza Costa Giasi who is the Caninos Locos chief scientist And she is also the research and development coordinator at LSITEC in São Paulo in Brazil So thank you for having both of you here And so I've been already talking about Caninos Locos a lot of in this little start And here you see kind of one of the first products coming out of Caninos Locos Some of you who are active in the hardware scene might have heard of our Labrador here on the right hand side It's a single board computer which is not only targeting makers but also industry And you see it is modular so there's some great thought which went into there And there has been a lot of focus on open hardware and open software in the design of this board But there's also a microcontroller that's the pulga or flea that you see here on the left side Which also has its roots in the Caninos Locos group And both of these boards and the experience we have built up with these boards Lead to the main and the core project we want to share here today in our presentation I will now hand over to Marcelo who is the wheel expert And can you tell more about how the ventilator was created? Okay, thank you Uli It's been a challenge for us working this project since the very early stages of the pandemic in 2020 In fact, our concerns about the pandemic started early in January Since we have a major tech conference in Las Vegas, CES We have the IEEE conference in consumer technologies And at that moment experts, engineers, professors, scientists at this conference It started to become aware and very concerned about the situation that started mainly in China Many professors from China at that moment didn't attend the conference So we come back to Brazil, quite concerned about it We start to do early discussions and then the first wave badly hit Europe and North America And then that was very scary, we are really worried And then by 15 March, professors at USP They start to join together efforts to do something related to ventilators At that moment we had a global movement of people, makers, universities Designing emergency ventilators And we have been approached by Professor Raul Lima Raul is an expert on lung physiological dynamics So he was the guy who really understand how to design a ventilator from scratch And that was the inventory that we had started on 19 March So what is a mechanical ventilator? A ventilator is a kind of equipment that is the only resource that we have to treat COVID Because COVID has a secondary condition that we call arts, acute respiratory distress syndrome And the only way to treat this killing secondary condition is using ventilator We should say that a significant amount of people that is dying from COVID Worldwide people are dying under this condition of being intubated using ventilators So suddenly ventilators became a fundamental piece of hardware to treat people And it's a very hard system to design, it's a very critical one Because any failure, any bug can lead for the patient death And worse than that, it's highly certified Certification agencies across the globe, Europe, Asia, FDA, US And Brazilian certification agencies are really, really careful about Making this equipment available in society In fact, in Brazil, like US, it is a crime that leads to 10 years in jail The improper design testing and use of ventilators without certification So considering this situation, we decide to build a ventilator That should be low cost for emergency situations When we say emergency is when we observe collapses, health system collapses We need to consider contingency needs where ventilators are not fully available to everyone And also we should consider this pandemic economy That is similar to a war time economy Where we have logistic pitfalls, material shortages, embargoes, politics, corruption And now other associated problems that will block citizens having access to these equipment So in our project, from scratch, using very common and widely available maker technologies Laser cutters, 3D printers and open source platforms In less than 120 days, Eliza will properly talk more about that We had designed more than seven boards in several configurations Because we are pursuing this certification And also including requisites in real time We basically said we are fine building the plane But we are very fortunate because in around 100 days from scratch We have a fully certified device So which are our design assumptions? The first assumption that we have is that eventually we will not have Compressed air in remote and poorest areas of Brazil in South America So Inspire is a ventilator that can generate compressed air by itself We like to have a low cost product, robust, biocompatible Very fast manufacturer of the shelf components Easy maintenance, fully certified by our means of health Fully validated in terms of functionality Because again, when we plug this ventilator on a human That is again the only source of life for a given patient If I would like to repeat, if the ventilator stops In few minutes, the patient will die immediately We need to work on very hard operation conditions 24 hours a day for 15 days or more And as much as we can But we need to observe the local regulation We need to keep this project using open hardware and open projects So in our case, we did what we call a cyber-physical approach We did an adaptation of what we call a manual resuscitator Or usually we call AMBO AMBO is a close artificial representation of the human's lung So if we can have precise algorithms That can deliver exactly the amount of air and oxygen to the human's lung And remove CO2 We can keep life-sustaining and we can eventually cure the patient Because then we can observe what we call the lung's dynamic complexity The concept that we had was very simple We just have an AMBO Compressed by a high precision digital step motor Using micro steps Because again, the lung is very, very sensible We have precise sensors We have a touch screen And that's it Everything else is plastic, aluminum and 3D printing parts So here is our maturity level evolution From scratch in 15 March By August we had approval And in October we started fabrication distribution We go through our certification steps So we tried open animals, pigs And also we tried open humans We just completed another round of trial Where we tested the ventilator again Open 40 patients in our clinical hospital So here is the technical effects of version B That was certified So we have independent buttons We have seven touch screen We have on-off buttons We can drive inspired by automotive batteries Yes, you can grab the nearby truck or car Plug in the spire And the spire will work for several hours Minimum requirement using motorcycle batteries is two hours At this moment our team is embedding a new battery That can operate the ventilator for eight hours And lies that team need to adapt these functional requisites every day Every day we have a new thing to modify So that is version B And then based on our lessons Distributed in ventilators around Especially with nurses Intensive care units across the whole country We did version C That is a little looks a bit more like an apple iPhone It's much more soft We have round surfaces And it's much easier to clean it But we did more and lies that we exploit that a bit better But version C We have internet, Wi-Fi, Bluetooth, GPS, Loro One HL7 and local AI support So at this moment we have distributed up to date 147 ventilators entirely in the whole Brazil We joke that we are the seven cavalry Because we used to arrive When there is absolutely no another resource Basically the distribution that we show it to you here Is the collapse health system map of Brazil Thank you very much to you, Marcelo I think when I first saw this project I was so impressed and I think there's so much knowledge In so short time reflected in there And I can't wait to hear from Liza About the future and where this is going Yeah, the situation here in Brazil Is really complicated now And we are having this big pressure In order to deliver the ventilators as soon as possible We could deliver already around 150 But we have plans to deliver 1,000 And our design team now is improving the production And test procedures in order to have Short-term manufacturing time But relating to the evolution of the project We have a roadmap And regarding the evolution of Panino's Logs Program As well We haven't been working in improving The system software reliability in many ways One of our efforts For example is to simplify the software update mechanism What will help us to have this shorter production time And updating the system more easily Regarding the other evolution What we have now with our ventilator Is a license from our health agency That is for emergency and transitory use Next step is to apply for magical equipment Plus A that we can use in hospitals And magical equipment plus B That is required for use in domestic Or on domestic environments and in ambulances You can see here some requirements for these certifications What we have to evolve in order to get class A and B Is to have a more complete case of ventilation modes And to be more reliable to electromagnetic interferences And also to have less electromagnetic emissions I'm showing here the level of emissions That is allowed in each class And our current emissions And our goal is on the other dimension Where we are not passing above these lines And we have already reviewed projects for this And now here is this new board And we are doing the tests and evaluations in this week So it's going right now A little bit slower because of this pressure To produce the ventilators But we are still going on with this line Other evolution that we have in mind Is to make the ventilator connected So InSpeedy is ready to be fully connected In a variety of technologies It will allow to explore big data processing To develop more efficient treatments We are planning to use artificial intelligence To analyze the relationship of ventilator configurations Drugs used, the patient profile And how the disease is evolving And it may extract valuable information For fighting the disease in the future So this is an important line That we are working for next step in the ventilator And regarding the Canineus Locus Evolution We have a complete roadmap So we have higher performance platforms Always focusing on the edge computing But still with more capability We have some that are more focused For artificial intelligence But the most exciting project That we are conducting now Is about developing our chipset for PUGA That is our low power, low cost and autonomous platform So we are doing it And we believe it will be a great advantage For the program and to use in the Internet of Things Liza, thanks so much I think the future still looks challenging But the future looks also like It is worse kind of digging into these challenges And I think we have already proven That you have the capability To shape the future in the way you are envisioning it I think everybody here including me Will wish you a lot of luck in moving on I'm looking forward to work with you in the future again But of course we are presenting here at ForceAsia To disseminate what we are doing here So do we want to actually reach out And get of course input from the community Because building the community around this And impacting the world is one of our goals Thank you for staying with us until this point And we will have some time now To answer some questions directly But the administration of ForceAsia has ensured us That we also have a public room Where you guys can continue asking us What is going on or getting in touch with us But even if you don't manage there To get in touch with us So please kind of go to Kanino's Locos Join and follow us there We are reporting news there When we get some time to actually do that If you want to promote us Then of course that is also very welcome And everything helps here And maybe when we beat the pandemic There will be chances of actually meeting in person And we would of course encourage you After reaching out to us Or if you happen to be on an academic exchange Either in Brazil or Estonia To get in touch with us Or if you are a company That is interested in what we are doing Then of course we are also very interested In industrial connections for the future Yeah, if you can't manage to set it up now In the questions or in the talk Please reach out to these contact addresses here And set up a virtual coffee with us Or suggest a project and get in touch And let's hope that this was not The last time that we see us But just the first And we will have many more meetings In this community Again in the future All right, thank you very much Forgot to say that Ulrich is Kanino's Locos Ambassador And Software Engineer Professor At the University of Tartu in Estonia Marcelo is Kanino's Locos Founder And Inspire Project Coordinator Professor at the Electrical Engineering at the University of Sao Paulo, Brazil And Liza is an R&D Coordinator At LSE Tech in Sao Paulo, Brazil And Programmer Kanino Locos Chief Scientist Let's have a We have some time for questions So let's go with that There was a first question on the chat Asking if you guys can explain a little bit more On what are the different parts And how they work together Yeah, I think it would be best if Marcelo directly talks about it So Marcelo, if you unmute yourself Can you kind of say something about the components again That are making up that You still are muted Okay, thank you Well, we try to keep the system very simple We basically have four parts Display Where we show what we call the breath maps So we can display The breath in curbs Oxygen level Frequency Basically that are the three parameters Seems to be simple But the lung is very fragile Enemy's take Pumping air to the human Lung can create Severe damage That can lead for infection too So, but anyway, we have the display The second part is the Step motor That pumps pressure the humble We decide to use step motors Because they are really precise And this precision is also important To generate the correct curves Then we have the single board computer We are using can in those locals We can eventually use another single board computer Eventually are ruins and others And in this single board computer We have also precision air sensors 12-bit high speed So these sensors they close the loop So we pump air we measure the lung response So basically that are the The parts on the ventilator Then the critical thing Is the software behind The software Implements a unique Close loop control techniques That we will publish sometime And these closed loop techniques Are related to the lung's physiology And that came from experts On lung physiology down here But in overall speaking The system is very simple Four parts display step motor Unbowl and computer All pieces together Could I think you are muted There are more questions I see here So are you moderating them Yeah so I think Roland has a question Who wants to ask Yeah this is a sort of open source collaboration question Have any other projects Get up your design your software And use them in their own environment For example seeking certification From their own regulator Yeah that's something that Make us a little bit disappointed Because the regulation here Is very very strong For example Unproper management Design of ventilators Give 10 years of jail So the regulation is really really strict So we have an understanding From the legal department of the university That if someone Do an improper copy Of the ventilator design And someone die The original Walters are the main The main responsibles for that So Not the person who made the copy and used it The designers The designers because the designers got the certification So what we did We start to limit the access of the project To a close community This is a partnership with us And under the hurry of delivering the ventilators Because we are At this moment we have probably in Brazil 300 people using the ventilators Yesterday for example I spent the whole day In the Navy base here We are trying to produce more 50 ventilators So we have these aware Of not having professors being jailed here Because we are being almost jailed in October You know companies Seeing our open movement Start to consider suiting us And that means that in 24 hours we can be jailed For eight years So that is the scene that we need to I am insisting on this Thank you for this question Roland We never designed it From seeing so critical In terms of life sustaining And when we opened this door We had discovered That the environment is very strict Related to certification Somehow that is understood Because we are saving lives And when we turn the ventilator That is the only Thing that is sustaining life of someone So if there is a bug or anything You kill the people You kill the person But also there are secondary liabilities Related potential damage That you can do to someone's lung So because what we call Class C Human sustaining critical devices That is the certification that we got Law is very strict And law somehow clashes With our vision of open source I am a super advocate of open source But they came to me October and said Hey professors You have two options You can be jailed And that could happen very soon Because some commercial companies are blaming That you guys are doing something open source And that is not proper Or we momentarily closed it At this moment We have 250 volunteers And the project is open to all these guys But we passed away the message That we have these A legal situation As soon as the things tend to come down We want to address it again To see if we can modify the law To allow more open stuff in this arena Anyone who is getting talk to with us Hospitals Research departments of some companies We are talking openly about that But we cannot put in the public domain Because if that happens And someone do an improper Use of the ventilator And someone die or get hurt The guys who got the final certification In our federal agency Could be Could be jailed Wow Good luck I think it was the most core question That can be asked here And I think one of the main reasons Why we are here at Fossage RL Because I think only this community And only with this outreach We can in the future address such questions Because if we want open hardware To make an impact We have to address these questions At one point And so if you guys have ideas, contacts To move that forward Please follow up with us And a profit from our experience But also let us profit from your experience there A lot of observation before I Move my face from the session A very similar problem exists With tools that are doing things That encroach into legal advice So a friend runs a startup in computational law And there's always this risk That a thing that produces a template contract For example Might be something that somebody argues Was legal advice And therefore that they relied on it And this caused bankruptcy Not death thankfully Which caused a bankruptcy And they then want to go back and sue The people who published the template Or published the tool that populates the template And so there's Fortunately, this has been going on on the internet for decades There's a gradually evolving understanding Of the difference between Someone publishing a thing Which is a sort of legal tool Versus someone taking on professional obligation To say I am a licensed professional of this area I have examined your case You have retained me as counsel And under those three conditions I advise you X So to maintain that separation Has been the answer for a lot of legal tech Make absolutely clear That the thing that looks like a thing That for basis of lawyer does not You still need legal advice to rely on I suspect that something similar May apply in your situation But it's a large complicated animal And it's not just money, it's lives So there's reason for conservatism May I accept that I will yield the floor Because I know there's at least other questions to come And I'm not the narrator So thank you Yeah, thank you for the question Roland And yeah, this is a very interesting topic We could go on and on on it And it's very nice that you guys are addressing it There's a little excitement here There's a lot of people Kelvin Tan saying this is very inspiring Amazing speed of the product In iterations and design And then there's another question asking Can you give an insight of why features Like Bluetooth and local AI supports And version C of the ventilator are actually needed Don't they make the challenge Of power management harder? Yeah, that is a very nice question Thank you also One thing that we learn, unfortunately People using ventilators, unfortunately die And we do believe that happens Because the health team sometimes They need a remote support To proper ventilate And patient So we enhanced our ventilator with a lot of connectivity features Like Bluetooth, Wi-Fi, high speed internet Because we are moving on towards collecting data From the ventilators For big data and AI analysis So that is exactly the point Where our research teams are working at this moment We are commissioning a super server at USP And very soon we hope to start to collect this data We do believe that in future Eventually AI will help tuning the parameters of the ventilator To save more lives That's why we have all these kind of connectivity features We put Bluetooth, Lora, Wi-Fi, Internet and GPS Thank you Nice, thank you very much There's also a question saying there was a talk of using Diving mask in ventilators Where face mask parts are unavailable Is that a possibility? Have you guys considered using Diving Mask? Well, when we design our ventilator here We are on economy for war So most of the hardware parts that we had used Are standard maker parts that we can't find everywhere Another thing that we need to face Is the certification So during the process We did, for example, on the single board computer We did seven designs to adapt the requisites To the certification specifications here But what we learned is that in this approach We can use local parts And in the end we have a super low cost ventilator Usually a ventilator here costs something like $20,000 And we can do a ventilator using this approach With less than $1,000 All right, yeah, thank you very much That makes a lot of sense There's many, many, many more questions coming up But we don't have, I'm afraid that we don't have that much time Would you guys be available at the discussion room So people can address these questions on the side That'll be great All right Yeah, okay, so Marcel and I will head over to the discussion room We'll hang out for another half an hour or so there And so please feel free to engage with us directly All right, perfect, thank you very much Yeah, great, amazing project, very exciting Thanks a lot, thank you guys Okay, meet you later Yeah, see you later I'm heading over to the discussion room Yeah, everyone that has questions please head to the discussion room They will be there to address your questions And all of those that are still pending Please go there, thank you Thank you for your presentation