 This research found that approximately one-third of participants in clinical trials were from rural areas, while only one-fifth of the general population lived in rural areas. Additionally, rural residents travelled farther to participate in clinical trials than their urban counterparts. However, the study associated risks were not associated with the distribution of rural and urban participants in trials. This article was authored by Adil Ibarucha, Chung Illinois WI, Sushmita Grama Srinivasan and others.