 The novel coronavirus of zoonotic origin, SARS-CoV-2, has recently been identified in patients with acute respiratory disease. It is structurally and genetically similar to SARS and bat SARS-like coronaviruses. The sudden increase in cases of coronavirus and its genetic sequence has provided us with an unprecedented opportunity to conduct bioinformatics and genomics analysis on this class of viruses. Clinical tests such as PCR and ELISA are urgently needed for early identification of infected patients. Unfortunately, these tests are expensive and not readily available for point of care, POC applications. This poses a serious challenge in the fight against COVID-19. To address this issue, we present a brief overview of the general features of coronaviruses and describe various amplification assays, sensing, biosensing, immunosensing, and apta-sensing for the determination of different groups of coronaviruses. These sensing and biosensing techniques developed for the detection of various classes of coronaviruses are useful in identifying the newly emerged coronavirus. This article was authored by Yasin Orji, Hessemadan Sarabi, Neyma Hemmat, and others. We are article.tv, links in the description below.