 AIM, Besitz disease, BD, is a systemic immuno-inflammatory disorder and the etiopathogenesis is to be specified. Cytokines play a role in immune response and in many inflammatory diseases. The aim of this case control study is to investigate serum pro-inflammatory cytokine tumor necrosis factor, TNF, alpha, interleukin, 1-beta, Illinois, 1-beta, soluble Illinois, 2-receptor, SIL, 2-R, Illinois, 6, and chemikine Illinois 8 levels in patients with BD. We also determined the end product of lipid peroxidation, malondialdehyde, MDA, in BD patients as an index for oxidative stress. This article was authored by Jim Everry-Cleo Glue, Ham Diyer, Yusuf Turcours, and others.