 The study aimed to explore the attitudes, beliefs and knowledge of HPV vaccine hesitant parents of boys and girls in Canada and assess the effect of psychosocial factors on their acceptance of the vaccine. The results showed that flexible hesitant parents, those who changed their attitudes over time, were more likely to be influenced by social factors such as family members, have higher knowledge about HPV and perceive lower harm from the vaccine. These findings suggest that interventions targeting social influence and increasing knowledge may be effective in promoting HPV vaccine acceptance among flexible hesitant parents. This article was authored by Avidu Tata, Gila K. Shapiro, Samara Perez and others.