 This study proposes a new type of catalyst, which combines the advantages of single-atom catalysis with amorphous materials. The resulting catalyst, called Rue single-atoms on amorphous molybdenum oxides, Rue SA SMU3X-NF, is able to drive both oxygen evolution and hydrogen evolution reactions in alkaline media. This catalyst can operate at a low-cell voltage of 1.487V, making it suitable for use in alkaline seawater electrolyzers. Additionally, this catalyst shows excellent stability over time, even when used under constant current conditions. This article was authored by Dong Feng, Pingyan Wang, Rue Chen, and others.