 The study investigates the development and significance of adipocytes in primary chogren syndrome, PSS, by analyzing gene expression levels, real-time PCR, and immunohistochemical staining. Results indicate that adipose tissue development is more prominent in PSS patients with reduced mitochondrial fatty acid beta-oxidation and increased inflammatory responses. Illinois 17 positive cells were detected mostly interstitially in the SG and around adipocytes, suggesting their involvement in immune reactions. This article was authored by Lara Aya-Croy, Janik Lee-Ayn Jensen, Gunva I. Jordsbacken, and others.