 This study investigated the association between the donors and recipients ACEI slash D gene polymorphism and risk of acute rejection outcome in renal allograft recipients. The observed allele frequencies were 2,9.8 percent, Id 35.1 percent and Dd 52.7 percent in donors and 2,9.8 percent, Id 35.1 percent and Dd 52.7 percent in recipients. No significant association was found between ACE genotypes and acute renal allograft rejection. Further research is needed to confirm these findings. This article was authored by Jalal Azmandian, Mohamed Amir Mohamedafar, Sarah Romanian Koshkaki and others.