 This study investigated the potential of three plant extracts, olive leaf, chamomile flower, and red tomato fruit, to synthesize zinc oxide nanoparticles, ZNONPs. The results showed that the synthesized ZNONPs exhibited a distinct size distribution and possessed antimicrobial activity against Sanfamona's ORIZPV. ORIZI, ZOO, STRENG GZ0003. Furthermore, the bacteria's cell membrane, biofilm formation, and swimming motility were also affected by the ZNONPs. These findings suggest that the synthesized ZNONPs could be used as effective bio-control agents for combating bacterial leaf blight diseases of rice. This article was authored by Solobomio Leitanogonimi, Yasmin Abdullah, Muchin Zhong, and others.