 Hypoxia is a common consequence of sepsis, which is the leading cause of death in intensive care unit, ICU, patients. This study examined whether the expression levels of certain genes regulated by hypoxia could be used as novel biomarkers for sepsis prognosis in ICU patients. The researchers found that the expression level of the gene encoding the enzyme hemoxygenase 1, HMOX1, was significantly higher in patients who developed sepsis or septic shock than those who did not. Furthermore, the gene's expression level was associated with the likelihood of developing sepsis or septic shock. Therefore, the researchers concluded that HMOX1 may serve as a useful biomarker for predicting the risk of sepsis and septic shock in ICU patients. This article was authored by Nikolaus S. Lotzios, Chrissy Kaskinidou, Edison Jahaj, and others. We are article.tv, links in the description below.