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Published on Feb 19, 2014
Table of Contents: 00:09 Lecture 2.7: Beating the Diffusion Limit: Enhanced Diffusion and Fluid Flow 02:02 Outline 02:51 Diffusion in multiple dimensions 06:47 Fast diffusion in multiple dimension 08:52 Fast diffusion in multiple dimensions 10:39 Aside: Inspirations 13:03 Outline 13:12 Sensor embedded in a flow channel 15:48 Total flux to a disk with fluid flow 17:34 Derivation: Sensors in flow (1) 19:35 Sensors in flow (2) 20:39 Sensors in flow (3) 22:12 Sensors with flow (4) 23:08 Outline 23:10 Total flux vs. flow 24:46 Relative enhancement of flow vs. size 25:10 Flow past a hemi-cylinder 25:45 Conclusions
This course provides an in-depth analysis of the origin of the extra-ordinary sensitivity, fundamental limits, and operating principles of modern nanobiosensors. The primary focus is the physics of biomolecule detection in terms of three elementary concepts: response time, sensitivity, and selectivity. And, it potentiometric, amperometric, and cantilever-based mass sensors to illustrate the application of these concepts to specific sensor technologies.