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Published on Feb 19, 2014
Table of Contents: 00:09 Lecture 1.2: Nanobiosensors Introductory Concepts: Biomolecules 00:50 Outline 01:42 Introducing the target 03:31 Biomolecules 05:11 Variety of target biomolecules 05:57 Small biomolecules: Glucose 07:04 Biopolymers: DNA (deoxyribonucleic acid) 09:54 Biopolymers: Protein 12:10 Protein Biomarkers for Cancer 13:12 Viruses 15:14 Bacteria 16:18 Example: How many molars in a 1000 mg Headache medicine? 18:03 Example: Importance of Sample Volume 20:33 Untitled: Slide 14 20:53 Diffusion Process -- Why random walk 23:05 Diffusion Distance 24:29 Conclusions
This course provides an in-depth analysis of the origin of the extra-ordinary sensitivity, fundamental limits, and operating principles of modern nanobiosensors. The primary focus is the physics of biomolecule detection in terms of three elementary concepts: response time, sensitivity, and selectivity. And, it potentiometric, amperometric, and cantilever-based mass sensors to illustrate the application of these concepts to specific sensor technologies.