 The human intestinal microbiome is composed of over 100 trillion microorganisms, mostly bacteria, which outnumber the host's own cells by a factor of 10. These microbes reside in the gastrointestinal tract, which contains up to 80 percent of the body's immune cells. This complex relationship between the host and their microbiome is essential for maintaining healthy immunity and preventing disease. When this balance is disturbed, it can lead to inflammatory diseases such as cancer. Recent research suggests that alterations in the gut microbiota can contribute to the development and progression of certain types of cancer. Therefore, understanding how these microbes affect the host's immune system could provide insight into novel therapeutic strategies for treating cancer. This article was authored by M.R.H.Assary, M.R.H.Assary, Tahani Baksh, and others.