 This paper discusses the potential of personalized 3D printed medical devices based on the author's experience in functional user assessments and material selection, design, optimization, and production and testing of multiple generations of different upper limb exoskeletons. The authors highlight the possibilities and limitations of personalizing the upper limb exoskeleton and provide directions for future research. This article was authored by Dariush Mikolayevsky, Isabela Rocek, Piotr Kotlarz, and others.