 Welcome to the Stop COVID-Dets webinar series brought to you by the University of the Philippines. The Stop COVID-Dets shorts make it easier for you to go to the presentations that you are interested in. I'm Dr. Raymond Sarmiento, Director of the National Telehealth Center. And I'm Dr. Susy Pineda Mercado, Adjunct Faculty of the National Telehealth Center. Together, let's stop COVID-Dets. I would like to thank you very much for giving us a chance to present yung maginago ng UPCBOL team. And later on, you will find out kung ano ba talaga ang UPCBOL? Okay. So I will start off with this slide. Almost all medical devices present in developing countries have been designed for use in industrialized countries. Consequently, they are often unaffordable and are maladapted to low resource settings. So these were statements made 10 years ago. But up till today, I don't think things have changed very much. So take a look at this equipment, etima biomedical equipment and devices, some of which you are very in need of during the COVID pandemic. Pero, if you look at these devices, everything is imported. So is it any wonder why we always don't have enough? Why we always can't afford them? And worse, pag nasira yung spare parts, hindi siya available. So ang question ninyo is why don't we go ahead and make them? It requires engineers and scientists on the one hand. It requires clinicians and healthcare workers on the other hand. But most importantly, it requires for them to work together. And even if there are packets of these individual teams working and successful on innovations, so far wala pa talagang mature na institution which allows this kind of collaboration. I think there are, for example, sa Lasal, has already taken initiative to come up with what they have now called the Institute of Biomedical Engineering and Health Technologies or IBET. And then of course, there's a Philippine Biomedical Innovation Consortium. But aside from those, wala talagang ibang mga collaborations like that. And that separation between the engineers and the healthcare workers is evident even in our own institution, the University of the Philippines. So nasa diliman yung engineers and scientists, nasa manila yung mga clinicians, parang nakaseparate by the Big Pasig River. So we never really get to collaborate with each other. In March of 2019, that's when the opportunity started. Ang UP Diliman College of Engineering, TTBDO director at that time si Michay Pasha, got in touch with UP Manila asking for clinicians to collaborate with some of their engineering proposals. And on our side sa UP Manila, the request was sent to the NIH director, but to avoid the horrendous traffic of going to Diliman, ang ginaan namin ng teleconference kami. And lo and behold, the teleconference was successful. So in April 2019, we went to the College of Engineering sa Diliman and doon nagpresent kami ng mga medical problems requiring engineering and science solutions. And that was very successful and in May ang nangyari was we invited the engineers and the scientists to visit sa PGH para makita nila exactly what's going on. These are the things that they needed to help us innovate on. And as a result of that, through many, many months of collaboration, we came out with four collaborative projects under the program which was then Christian Siebold. So this is the UP Surgical Innovation and Biotechnology Laboratory. And this program proposal was submitted to the DO-STPHRD and ang Christmas gift sa amin ng DO-STPHRD was we were given a grant to start this program. And this is on your left hand side. Kita mo yung grant na binigay ng DO-STPHRD. And so ang next step really was to come up with a MOA. So nagsainan ng MOA between DO-ST and UP Manila, pero not all good things can continue like that. So ang nangyari as we all know COVID struck. And sunod-sunod na yun. Soon we were on complete lockdown. And worse than that, so many of our comrades fell. We saw so many people falling along the side. And very often it was because of lack of protective equipment. Lack of distancing, lack of different mechanisms to protect our healthcare workers. So at that time, SIBOL was recently born. So while there was a MOA, wala pa yung tera, no infrastructure, no equipment. But that was our reason for being. SIBOL had to do something. And even if we didn't have the money and the infrastructure and equipment, we had two things. We had Viber and we had Zoom. By June of 2020, we were convened. We convened ourselves in March of 2020. And in three months' time, we had 11 projects. And these 11 projects were divided into three teams. Basically to protect, to disinfect, and to distance. So etiyong three teams and their 11 projects. And you will notice that each of the projects is handled by an investigator and a co-investigator, one of which is a clinician and the other one is either an engineer or a scientist. And so you have the PPE team, you have the disinfection team, and you have the telemonitoring team to do those three thrusts that we had. And sa umpisa, since, siyempre, the money was not there yet from the initial program, we had no money and we looked for funding. And we approached the OSTPC HRD and they were very, very helpful. They were going to give us grants for each of the different proposals that we had. But then, no matter how much you expedite this kind of a process, siyempre, hindi man agad-agad po punta yung mga kakakawa tayo ng para for that purpose. So we relied a lot on private sponsors. And here, I do have to thank my classmates from high school. The savior high school class responded by donating and their donations were the initial funding for the seed money for our initial prototypes. So here on the right hand side, you see some of these prototypes and some of these projects, later on, three out of the four projects here, you will be hearing from their inventors and innovators. So here, I gave you an idea of how the SIBOL team came about and kung anyong purpose ng SIBOL team. So it's a surgical innovation and biotechnology laboratory. Ang purpose namin really is to innovate, invent, and create locally made biomedical equipment and devices using local expertise and locally available materials. So you will be hearing this morning more about these products. So I will start off with one of these products and the project that I am deeply involved with is called the SANiPAD. So eto yun. Anong SANiPAD? You heard doctora April Lianeta from the emergency medicine department talk about the SANiPAD. And so eto niyo may hita yung pictures of exactly what the SANiPAD is like. And here, before I start, I would like to recognize the co-investigators, the engineers starting from from Magdaluyo, my co-investigators, doctora Catherine Ko, engineer Pechardo, our industrial designer, August Pataksil, and our science research specialist, Jenna Gonzalez. So eto yung backgrounder. So kayo as healthcare workers coming out of heavily infected areas or COVID areas, nakapipe kayo. But when you're doffing the contaminated PPE, that is a source of infection, a source of contamination to the healthcare worker, to the safety officers, to the disposal service personnel, the people who clean up after us yung ating PPE, people have to dispose of it. So they will be exposed to it. So eto pa pasok may yung SANiPAD. So after the doffing, before the doffing, the healthcare worker goes through the SANiPAD. So the biomedical engineering solution here is to clean off the PPE before you doff. As it do, it protects the healthcare worker, it protects the safety officer, it protects eventually the disposal team, and the added bonus is ngayon nanduba dami na naman yung cases and kumukon na naman yung supply ng PPE, it addresses the short supply of PPE, because you can reuse them. Okay, so yung innovation, ang question natin is how are we different from all of these na ahita niya yung mga contamination tents, et cetera, ang yung difference na, namin, the SANiPAD is self-contained, no touch, so less chance of contamination. There are many mechanisms to decrease contamination. So there's a control release of disinfectants, there's an automated disinfection process, it's portable, it's intuitive, it's intuitive user, there's an intuitive user interface, it uses the HEPA filter, may shower, may irradiation, and like all the other projects in the UPC World program, they are based on science. Everything is evidence-based for safety and efficacy and all the other parameters. So we have the assurance to the user of the safety, the efficacy, and all of these have been tested by clinician, scientists, engineers from both UP Dilliman and UP Manila and they pass the international standards. So these are the basic features of the SANiPAD. Of course you have the frame, you have the door and mechanism, disinfection system, the HEPA filter, the UPC, the drain, the electricals, and the pathogen challenge. So what I'm saying here is kahit namanaming prototypes na, each prototype is based on these principles always. So eto yung prototype one. And eto yung prototype one, I will show you, this was at the time na wala kami interitalida. So this was an air shower from the college engineering kondem na. So this was converted kasi the healthcare worker entered and pati yung yung noise na, alam na alam nito na, kondem na air shower na inayos lang namin and ginamit namin for the SANiPAD. So from there we learned and then we went on to come up with the prototype two and some of these pictures show you the pathogen challenge for the disinfection. And here this is the SANiPAD situated in the department of doctora April Lyaneta and you will see one of their healthcare workers going in. So he goes through the disinfection process, may fogging, may blower, and then later on when he comes out, at the end of the year. So I want to show on this slide the evolution of an innovation. It's not something na from the first day pa lang pag naisip mo na and then that's it. You have a perfect beautiful SANiPAD. It doesn't work that way. So we started off with this sabi ko nga, condemned air shower na denonate lang sa amin and then they have the prototype two and then with further improvements and feedback from all the workers we are coming out with prototype five already by next week. And this is a quick rendition of prototype four and five. There you go. Looking at the exterior the exhaust and then as we enter yung interior yan yung ventilation. So with the fogging yan you will see that this pipe now leads into the cubicle. Now inside, once we get inside makihita nyo kung saan po mapasok yung disinfectant. There you go. And then later on makihita nyo sa taas makihita nyo yung blower. Yan. Okay. And then yan yung mechanism for the blower. Okay, we'll cut that short and go to the next slide which is really showing you na every time na may gumagamit meronin kaming mechanism for feedback. So it depends on the feedback ng healthcare worker is based on that naging improve ang prototype. And this really is a slide to show you what goes on. This is the work behind the scenes. So hindi siya like I said with one snap of a finger next day maganda na yung gawa. So we've gone through so many different prototypes so many different trials and errors. Gone through work with microbiologists, engineers, industrial designers even choosing how to test it, how to make sure na okay siya and then the pathogen challenges to make sure na everything is evidence-based. And of course the DOST now that we're using may the DOST fund yung team comes to converse with us and to communicate with us to make sure na everything is going fine. And this is a picture that we took last month when we visited our engineers at the triple M because in one of their sellers do namin ginagawa yung isang prototype. So these are our acknowledgements. We'd like to of course acknowledge our UP Manila Chancellor Menchit Padilla and our UP College of Medicine Dean Charlotte Cheong because they've been extremely supportive of all our work not just for the Sunny Pad but for the entire UP C-ball program. They're heavily invested in it. And acknowledgement goes to so many different people. UP Dileman, all the scientists and engineers, biochemists, biologists, engineers, technicians, then the of course the chair of the triple M na so UP Dileman then our UP Manila clinicians all the way from public health, medicine and then of course the entire Sunny Pad team. And we always will and the work is always dedicated to these fallen healthcare workers and those of you who continue to work so hard at the front line despite all the risks. Thank you very much from the UP C-ball program and for the project Sunny Pad. Thank you. We hope that you learn as much as we did from that excellent presentation. We also hope that you will join us every Friday from 12 noon to 2 pm Manila time on Zoom, Facebook or YouTube. So stay safe, stay connected and see you online.