 Layer double hydroxides, LDHs, have been developed as efficient drug delivery systems, DDS, due to their biocompatibility and ability to control drug release. Advances in synthesizing intercalated structures and modifying slash functionalizing LDHs have led to new biotechnological and biomedical applications, with recent progress focusing on DDS, with cardiovascular, anti-inflammatory, and anti-cancer drugs as guests. Future prospects for LDH-based drug carriers include continued research and development of novel applications.