 Good morning everybody. My name is Lucia Hindorf. I'm a Program Director in the Division of Genomic Medicine at the NHGRI. I'm one of the Program Directors that works on the Clinical Sequencing and Exploratory Research or CSER program, and I'm thrilled to welcome you to the joint CSER Emerge meeting today. Those of you that were at the last joint CSER Emerge meeting will remember that it occurred during a federal government shutdown, so I'm particularly pleased to actually be here in the room today with you all. So that's really just the starting point, that the program committee has done a fantastic job in identifying a number of sessions that are sure to be of joint interest to both consortia and speaking from the CSER standpoint, we've been thinking about these things for quite some time, so it's particularly special to have twice the brain power in the room to discuss and tackle these issues. So I'll turn it over to my colleague Rong Ling-Li right now.