1. Lecture 1. Infrared Spectroscopy: Introduction, Theory, Instrumentation, and Sample Preparation.

  2. Lecture 2. Infrared Spectroscopy: C,H,O-Containing Functional Groups.

  3. Discussion 1. Molecular Modeling with PyMOL

  4. Lecture 3. Effect of Ring Size Conjugation Electron-Withdrawing Groups

  5. Lecture 4. Mass Spectrometry: Theory, Instrumentation, and Techniques

  6. Lecture 5. Isotopic Masses, Isotopic Abundances, and High-Resolution Mass Spectrometry.

  7. Lecture 5A. Isotopic Masses, Isotopic Abundances, and High-Resolution Mass Spectrometry.

  8. Lecture 6. Fragmentation in EIMS: Alkanes, Alkenes, Heteroatom Compounds, Carbonyl Compounds.

  9. Lecture 6A. Fragmentation in EIMS: Alkanes, Alkenes, Heteroatom Compounds, Carbonyl Compounds.

  10. Lecture 7. Introduction to NMR Spectroscopy: Concepts and Theory, Part 1.

  11. Lecture 8. Introduction to NMR Spectroscopy: Concepts and Theory, Part 2

  12. Lecture 9. Chemical Shift. 1H NMR Chemical Shifts.

  13. Lecture 10. 13C NMR Chemical Shifts. Chemical Equivalence and Spin-Spin Coupling.

  14. Lecture 11. Magnetic Equivalence, Spin Systems, and Pople Notation.

  15. Lecture 12. Coupling Analysis in First-Order and Near-First-Order Systems

  16. Lecture 13. Coupling Analysis in First-Order and Near-First-Order Systems (continued)

  17. Lecture 14. Spin-Spin Coupling in Stereochemistry and Structure Determination

  18. Lecture 15. Coupling Involving Other Nuclei

  19. Lecture 16. The Importance of 13C Chemical Shifts in Structure and Stereochemistry Determination

  20. Lecture 17. Introduction to 2D NMR Spectroscopy

  21. Lecture 18. Dynamic Effects in NMR Spectroscopy

  22. Lecture 19. The Nuclear Overhauser Effect in Stereochemistry and Structure Determination

  23. Lecture 20. Understanding Complex Pulse Sequences

  24. Lecture 21. Using HMBC to Help Solve Structures: "Putting the Pieces Together"

  25. Lecture 22. Aspects of COSY, HMQC, HMBC, and Related Experiments

  26. Lecture 23. Using TOCSY to Elucidate Spin Systems. ROESY

  27. Lecture 24. Using Organic Spectroscopy to Solve Complex Structures

  28. Lecture 25. INADEQUATE. Some Thoughts on Homework Set 9.

  29. Lecture 26. Using Organic Spectroscopy to Solve Complex Structures, Part 2

  30. Lecture 27. Using HMQC-TOCSY or HSQC-TOCSY to Deal with Overlap

  31. Lecture 28. Some Other Useful NMR Techniques