 Access to safe water, sanitation and hygiene is fundamental in protecting health, which has been evident during the COVID-19 pandemic. In Mexico City, COVID-19 has presented a major challenge for those experiencing homelessness. The closure of public spaces, businesses and self-isolation at the height of COVID-19 has exacerbated various homeless people faced when accessing safe water and sanitation services. They are left with no safe spaces to urinate, defecate and take care of them and through needs. The private limited access to sanitation facilities, many resort to open defecation, creating immediate threats to their health, safety and dignity. While the closure of public facilities and businesses is an indirect consequence of the pandemic, it highlights the importance of the public services that are available and affordable to everyone, even in times of crisis. Toilets are essential services that have a direct impact on the health and dignity of all individuals. Access to sanitation is a human right that must be guaranteed.