 This systematic review assessed the effectiveness of remote patient monitoring, RPM, follow-up compared with standard care, for patients with chronic kidney disease, CKD, who perform dialysis at home. Seven studies were included, including three randomized controlled trials and five retrospective cohort studies. The studies showed low to very low certainty evidence that indicated there may be positive effects of RPM follow-up, in comparison to standard care only, for adult patients with CKD who perform dialysis at home. Offering RPM follow-up for home dialysis patients as an alternative or supplement to standard care appears to be safe and provide health benefits such as fewer hospitalization days. Future implementation should be coupled with robust, high-quality evaluations. This article was offered by Rigmor Seberg, Henriette Thysneigold and Lin Nguyen.