 When we find someone with kidney cancer, chemotherapy never works, and then they tend to be radio-resistant, although we do use radiation at higher doses to kill those cells, right? And then as far as treatment, medical treatment, to your point, in general we have these two groups, target therapy and then immunotherapy. Target therapy includes drugs that block the vessels, so we call that angiogenic drugs, anti-VHF. We also use other target therapies that we use in other tumors that are called mTOR inhibitors, and then the immunotherapies, as you said, the cancer cell tells our immune system, our good soldiers in the body, don't attack me because I'm a good guy, and then the soldiers in our body don't attack us. But then when you bring those drugs, those immunotherapy, they block that signal, so they allow our soldiers to look at the cancer cell, and even the cancerists trying to tell them, I'm good, I'm good, don't attack me, the good guys, the immune cells are going to still attack cancer.