 Phosphorylation is a key post-translational modification that is utilized in many biological processes for the rapid and reversible regulation of protein localization and activity. Polo-like kinase-1, PLK-1, is essential for both mitotic and miotic cell divisions, with key functions being conserved in eukaryotes. In kinohabditis elegans ocytes, PLK-1 plays distinct roles in miotic spindle assembly and or stability. Chromosome alignment and segregation and polar body extrusion during meiosis-1. Additionally, it was discovered that BUB-1 and CENPHC-P4 are responsible for recruiting PLK-1 to the kinetochore and mid-bivalent respectively. Disrupting either of these interactions leads to severe miotic defects, resulting in highly aneuploid ocytes. This study provides insight into the roles played by PLK-1 during ocyte meiosis and sheds light on its mechanism of action. This article was authored by Samuel J.P. Taylor, Laura Bell-Borgia, Flavie Subagu and others. We are article.tv, links in the description below.