 Radiosensitizers are compounds or nanostructures that can increase the efficiency of ionizing radiation in killing cancer cells. They also reduce the potential damage to healthy tissue from radiation-induced damage. This makes them useful adjuncts to radiotherapy treatments for cancer. Despite their potential benefits, there are still many challenges associated with using radiosensitizers, such as the difficulty of delivering them to tumors and the potential for side effects. Future research should focus on developing more effective radiosensitizer delivery systems and understanding how they interact with other cancer treatments. This article was authored by Muhammad Verzanda, Layla Sabiyuri, Vahid Mansuri, and others.