 This study examined the factors associated with drug-resistant epilepsy in patients who had experienced a stroke. It found that older age at stroke onset, intracerebral hemorrhage, severe stroke, latency of post-stroke epilepsy, PSE, greater than 12 months, and status epilepticus at PSE onset were all independently associated with increased risk of drug resistance. Additionally, an amogram was developed using these five variables which showed good accuracy in predicting drug-resistant PSE. This study provides valuable information about the risk of drug-resistant PSE in order to help physicians make informed decisions regarding treatment options. This article was authored by Simone Latanzi, Stefano Molletti, Eugen Trinka, and others.