 Emerging SARS-CoV-2 amicron sublineages B.A.4 and B.A.5 rays concerns about potential immunovasion. Show that both B.A.4 and B.A.5 are able to escape immune response induced by prior B.A.1 infection, but that this effect is less pronounced in vaccinated individuals. This article was authored by Khadija Khan, Farina Karim, Yoshika Gonga, and others.