 Bio-sensors are being used to detect viral infections in resource-limited settings. These devices have been developed to overcome the challenges associated with traditional diagnostics, including specificity, low target numbers, and biological matrices. However, there are still some limitations, such as detection limits, linear dynamic ranges, stability, and reliability. Additionally, economic factors must also be considered when deploying these devices in resource-scare settings. This article was authored by Jesarine Ceylon, Ozchikin Erdem, Serhat Yunal, and others.