 This study investigates factors impacting COVID-19 vaccine acceptance among Jordanians, finding that higher risk perception scores were associated with being female, young, or a smoker, and that male participants, participants aged 18 to 24 years, and those with children under 18 years were more willing to get vaccinated. Policymakers are recommended to develop public educational campaigns to enhance trust in and willingness to take the COVID-19 vaccine. This article was authored by Mohamed B. Nuzer, Rasha Arabayat, Rohan Kasane, and others.