 And in fact, this is not limited to fundamental results in biochemistry and biophysics. We use this to understand some pretty severe diseases. It turns out that quite a few mutations in these voltage sensors leads to arrhythmia effects. And we might be able to treat that with compounds that alter the motions of the ceilings. In addition, certain forms of epilepsy also influence how these helices move, mutants in places where we shouldn't have mutated them in the voltage sensor. Exactly how this happens, we don't know yet. It's a very active field of research, but if we believe that this is caused by malfunctioning that the helix, and particularly if the rest of the voltage sensor can't open enough, maybe we could find a way to help it open more. How would you do that? Well, remember what I said about the electrostatics. If I could just put, these are four positive charges, if I could just put a negative charge up here, I might help pull them up a bit. But I can't just add a negative charge in a molecule randomly and make it appear in the right place. So the trick is that what if I had something that was almost a lipid? In fact, it is almost a lipid. It's a lipid chain, a fatty acid chain. But this fatty acid chain now has a negative charge on it. So if I pick the right fatty acid chain, it could diffuse to the bilayer, bind to the protein, and then I would now have a negative charge here that would pull it up.