 This study proposes a novel approach to treating degenerated intervertebral discs by developing a biodegradable scaffold with regenerative capabilities. The scaffold is made of a shaped memory polymer called polyglycerol decanoate, PGD, and is designed to mimic the mechanical properties of human intervertebral discs. Additionally, the scaffold is coated with a chemikine called stromal cell derived factor one alpha, SDF, one alpha, to attract stem cells from the patient's own body. This combination of features allows the scaffold to be used as a minimally invasive implant that can both provide support while also promoting natural healing. In animal studies, this scaffold was found to be more effective than other treatments at restoring disc height and promoting regeneration of the disc. This article was authored by Liz Hen Wang, Kai Xiang Jin, Nan Li, and others.