 Recent research has focused on understanding the role of regulatory T-cells, trigs, and myeloid-derived suppressor cells, MDSCs, in cancer. These cells are thought to play a key role in suppressing the body's immune system, allowing cancer cells to evade detection and spread throughout the body. However, it is now understood that these cells can be divided into different subtypes with varying levels of activity. This knowledge is essential for developing new treatments that can target specific types of trigs or MDSCs to improve patient outcomes. This article was authored by Belal Chaudhary and Iod L. Cord.