 The U.S. Clean Power Plan aims to reduce carbon emissions from fossil fuel-fired electricity generating units through various mechanisms, including residential energy efficiency measures that have important co-benefits. Simulating the economic, health, and climate benefits of increased residential insulation shows that this measure would lead to annual reductions of 80 million tonnes of CO2 from EGUs and co-benefits including 30 million tonnes of CO2 from residential combustion and 320-premitude deaths associated with criteria pollutant emissions. Money-aised climate and health co-benefits average 9 per tonne of CO2 reduced from EGUs, and state-specific co-benefit estimates can inform optimal clean power plan implementation strategies. This article was authored by Jonathan Ilevi, Makaewu, Stephanie L Penn, and others.